MHC-class-II are expressed in a subpopulation of human neural stem cells… What?
Expression of major histocompatibility antigens class-2 (MHC-II) under non-inflammatory conditions is not usually associated with the nervous system.
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Expression of major histocompatibility antigens class-2 (MHC-II) under non-inflammatory conditions is not usually associated with the nervous system.
Human somatic stem cells with neural differentiation potential can be valuable for developing cell-based therapies, including treatment of birth-related defects, while avoiding issues associated with cell reprogramming.
Human umbilical cord blood stem cells (HUCBSC) are potentially a very important source of stem cells for tissue repair, as their use would circumvent the ethical issues involved with embryonic stem cells.
In conclusion, this work suggests that the cord blood haematopoietic and nonhaematopoietic stem cell fractions are unable to generate neural progenitors, and should be avoided for neurotransplant therapy proposes at this stage.
The proper and ethical use of stem cells can benefit the one billion of people who are affected by neurological diseases worldwid